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KMID : 1189420050180030037
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Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology
2005 Volume.18 No. 3 p.37 ~ p.43
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Effects of Cytotoxic and Antioxidant of Methanol Extracts from Medicinal Plants
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Lee Jeong-Ho
Kim Yun-Kyung
Choi Mun-Il
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Abstract
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This study was performed to determine the cytotoxic effect of methanol extract from Houttuynia Cordata and Glycine soja. The cell viability was determined by MTT method. Their cytotoxic activities against three cancer cell lines such as A549, MDA-MB-231 and SNU-C4 cell line were tested. Among them, The methanol extract of Houttuynia Cordata showed the strongest cytotoxic effect against SNU-C4 cells. These results suggest that the methanol extract of Houttuynia Cordata possessed a potential antitumorous agent. The free radical scavenging activity using DPPH method was the strongest of Houttuynia Cordata methanol extract and ethyl acetate fraction.
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KEYWORD
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HouttuyniaCordata, Glycinesoja, A549, MDA-MB-231, SNU-C4, DPPH
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